Although innovation networks are widely adopted as an institutional template for organizational innovation, firms are readjusting technology strategies and reshaping innovation networks to tackle dynamic external challenges in today’s complex and volatile economic system. Disembeddedness from existing networks is increasingly chosen for innovation strategy restructuring, yet there remains a relative lack of theoretical frameworks and systematic literature reviews on this topic. In view of this, this paper combs through 99 authoritative journal articles on embeddedness and innovation networks, traces the origins of embeddedness and disembeddedness theories, summarizes embeddedness views in network research, and deduces the clues and logic of network disembeddedness. This process refines the dual-aspect framework of innovation network embeddedness. This paper also explores future research directions on the shift from embeddedness to disembeddedness in innovation networks from three aspects: driving mechanisms, impact mechanisms, and governance mechanisms. It offers useful references for enriching the innovation network theory and helping organizations adapt to complex innovation environments.